The Combination of Preoperative Pain, Conditioned Pain Modulation, and Pain Catastrophizing Predicts Postoperative Pain 12 Months After Total Knee Arthroplasty

Abstract Objectives Approximately 20% of knee osteoarthritis patients undergoing total arthroplasty (TKA) report chronic postoperative pain. Studies suggest that preoperative variables such as impaired descending pain control, catastrophizing, function, and neuropathic pain–like symptoms may predict 12 months after TKA, but the combined prediction value these factors has not been tested. The current prospective cohort study aimed to combine risk investigate predictive for TKA. Design Prospective with follow-up surgery. Patients A consecutive sample 131 Methods Pain intensity, Catastrophizing Scale (PCS) scores, PainDETECT Questionnaire conditioned modulation (CPM), Oxford Knee Score (OKS) were obtained before Results TKA improved (P < 0.001), PCS scores OKSs 0.001). Preoperative correlated (r = 0.38, P 0.53, –0.25, associated 0.001) 0.002). Higher was high 0.424, 0.33, 0.298, lower CPM –0.18, 0.04). combination pain, score, explained 20.5% variance in had a significant effect on trajectory when accounting patient (t 14.41, 0.0005). Conclusion clinical levels catastrophizing thoughts, long-term